The comprehensive proposal application will ask for the following information (if applicable):

• NIH Biosketch of proposing investigator
• Study rationale
• Hypothesis
• Primary objective(s) and endpoint(s)
• Study centers (proposed)
• Study population
• Study design
• Intervention/treatment
• Sample size estimate
• Timeline and length of participant follow-up
• New and/or unique assay
• External support/collaboration/funding
• Publication references
• Estimated costs in $ (direct)

Proposals will be carefully reviewed by the applicable ARLG committee. If you have not received a response from an ARLG representative within 6 weeks, please contact us at arlgsubmissionhelp@duke.edu.