TITLE
A Phase IV Open-Label Pharmacokinetic Study of Minocycline for Injection Following a Single Infusion in Critically-Ill Adults

Description
Characterize minocycline PK at the population level in critically-ill adults, with illness known or suspected to be caused by infection with Gram-negative bacteria. To assess patient-level and clinical covariates associated with minocycline pharmacokinetic properties in the same patient population.