CEF_BP

Ceftriaxone Breakpoint

TITLE

Multi-center gram negative database to establish clinically relevant antibiotic breakpoint interpretive criteria for Ceftriaxone

DESCRIPTION
A retrospective, observational propensity score-matched study of patients 18 years or older with monomicrobial Gram-negative bacteremia with the primary objective being:
to compare clinical outcomes of adult patients with Gram-negative bacteremia with organisms with minimum inhibitory concentrations between 4-8 µg/ml who received ceftriaxone compared with broader-spectrum antibiotic agents

BCID

Film Array Blood Culture ID Panel
TITLE

Clinical and economic impact of rapid identification and susceptibility testing of pathogens growing in blood culture bottles. (Note: seed grant is to support economic analysis portion of the study)

DESCRIPTION
A prospective, randomized controlled trial with the primary objective being to determine if the BCID test either alone, or in combination with antimicrobial stewardship, will impact the antimicrobial utilization, clinical outcomes, and healthcare costs of patients with bloodstream infections