The January 2022 issue starts the year off with news on ARLG Early Stage Investigator (ESI) Seed Grants, a streamlined protocol submissions process and webpage, and a spotlight on clinical trialist in training Nick Turner. Plus, get updates on events, study milestones, and more.
Author: susan.herron@duke.edu
Robin Patel Named by ISAC as 2022 Hamao Umezawa Memorial Awardee
The International Society of Antimicrobial Chemotherapy (ISAC) announced it has selected Robin Patel to receive the 2022 Hamao Umezawa Memorial Award (HUMA). Dr. Patel serves as ARLG’s Laboratory Center Director and is the Director of the Infectious Diseases Research Laboratory at the Mayo Clinic.
Dr. Patel’s work focuses on developing improved diagnostic approaches to combat antibacterial resistance, researching the mechanisms of biofilm formation, and designing and conducting studies for new antibacterial treatment options. Her numerous career highlights include serving as president of the American Society for Microbiology, a council member for the National Institutes of Allergy and Infectious Diseases, and an associate editor for the Journal of Clinical Microbiology. She has published more than 500 peer-reviewed publications.
HUMA, which is ISAC’s highest award, recognizes outstanding contributions in the field of antimicrobial chemotherapy by a researcher, scientist, or clinician. Dr. Patel will receive her award medal, certificate, and 10,000 Swiss Francs during the 32nd International Congress of Antimicrobial Chemotherapy (ICC 2022) scheduled for November 70 – 30 in Perth, Australia. She will deliver the HUMA plenary lecture on “Microbial Theranostics – A Resistance Combatting Strategy”.
Robert Bonomo to Lead Coordinating Center for VA SHIELD
The U.S. Department of Veterans Affairs (VA) selected Robert Bonomo as the Director of the Coordinating Center for the VA Science and Health Initiative to Combat Infectious and Life-Threatening Diseases (VA SHIELD), a cental biospecimen and data repository.
Dr. Bonomo is Chief of the Medical Service and Director of the Geriatric Research Education and Clinical Center (GRECC) at the Cleveland VA Medical Center as well as a member of the ARLG Laboratory Center Consortium Team. His work in antibacterial resistance includes research on the mechanistic basis of resistance to beta-lactam antibiotics and beta-lactamase inhibitors, the molecular epidemiology of multidrug resistant Gram-negative bacteria, and the implementation of molecular diagnostics in clinical care of patients with infectious disease. Dr. Bonomo has received more than 70 honors and awards including the 2020 Mark Wolcott Award for Excellence in Clinical Leadership.
The VA SHIELD houses specimens and data related to COVID-19 and other emerging diseases to help VA investigators and other collaborators develop diagnostic, therapeutic, and preventative strategies for use in clinical care. The new initiative will support the VA’s national emergency preparedness efforts by helping to facilitate a faster, more coordinated response to emerging diseases.
“By understanding emerging disease data as it relates to large patient populations, VA can accelerate its research efforts to combat future outbreaks in a more coordinated, expedited fashion,” said Dr. Bonomo. “The Coordinating Center of VA SHIELD will be responsible for positioning VA to respond rapidly to national and international biological events and threats and to substantially contribute to clinical research and development”.
ECCMID 2022 On-Demand
Catch ECCMID 2022 while you still can! Your registration includes access to on-demand content until July 26, 2022. To help you plan, we’ve highlighted some presentations and speakers you won’t want to miss. Also, mark your calendars for May 19, 2022. Post-ECCMID online learning day, which is on the topic of Antimicrobial Resistance and Stewardship, is free for ECCMID registrants. View the Post-ECCMID Programme
| Day | Time (CEST) | Session # and Title | Presentation # and Title | Speakers |
|---|---|---|---|---|
| April 23 | 16:15-18:15 | EW053 Educational Workshop Opportunistic infections of the central nervous system | WO219 Infections of the CNS in solid organ transplant patients | Judith Anesi |
| April 25 | 7:15-8:15 | ME125 Meet the Expert ESCMID and IDSA treatment guidelines for MDR Gram-negative bacterial infections | MO532 | Pranita Tamma |
| April 25 | 8:30-10:30 | SY136 Symposium ESCMID Guidelines for the treatment of infections caused by multidrug-resistant Gram-negatives: a case-based approach | SO583 Cases of multidrug-resistant P. aeruginosa | Robert Bonomo |
| April 25 | 13:30-14:30 | SY163 Symposium Recent top papers in transplant ID and haem/onc ID | SO678 SOT-ID | David van Duin |
| April 26 | 7:15-8:15 | ME189 Meet the Expert Azole-resistant Candida parapsilosis: a new nosocomial threat? | MO776 | Mariana Castanheira |
| April 26 | 7:15-8:15 | ME191 Meet the Expert Duration of therapy: from what we know to what we do | MO780 | Angela Huttner |
| April 26 | 7:15-8:15 | ME194 Meet the Expert How I treat severe Stenotrophomonas maltophilia infections | MO787 | David van Duin |
| April 26 | 19:15-20:45 | EW229 Educational Workshop Behavioural science essentials for antimicrobial stewards | WO937 Antibiotic prescribing as a decision-making process | Sara Cosgrove |
ARLG at the Texas Medical Center AMR & Stewardship Conference
ARLG experts will deliver presentations on a variety of topics during the 5th Annual Texas Medical Center AMR & Stewardship Conference. The event will take place online January 19 – 21. Use the guide below to help plan your conference sessions.
ARLG AMR & Stewardship Conference 2022 Sessions
| Day | Time | Session Title | Presentation Title | Moderators | Speakers |
|---|---|---|---|---|---|
| Jan. 19 | 7:30 - 8:20 a.m. | Career Mentoring: Clinical Scientist Pathway | Sam Shelburne | ||
| Jan. 19 | 8:40 - 8:45 a.m. | Welcome | Cesar Arias | ||
| Jan. 19 | 8:45 - 9:10 a.m. | ARLG and the Future of Clinical Research in Antimicrobial Resistance | Vance Fowler | ||
| Jan. 19 | 3:30 - 4:30 p.m. | Session 4: NIH Antimicrobial Resistance Leadership Group (ARLG) Early Stage Investigators | Anthony Harris, Henry Chambers | ||
| Jan. 19 | 3:30 - 4:45 p.m. | DOOR analysis and cUTI | Jessica Howard-Anderson | ||
| Jan. 19 | 3:45 - 4:00 p.m. | DOOR Endpoint Analysis in Intraabdominal Infection: FDA-NIH Collaboration | Tori Kinamon | ||
| Jan. 19 | 4:00 - 4:15 p.m. | DOTS Trial: Dalbavancin as an Option for Treatment of Staphylococcus aureus Bacteremia | Nicolas Turner | ||
| Jan. 19 | 4:15 - 4:30 p.m. | PHAGE Trial | Maria Souli | ||
| Jan. 19 | 4:30 - 5:15 p.m. | Session 5: Selected Abstracts | Sam Shelburne | ||
| Jan. 20 | 8:30 - 9:45 a.m. | Session 6 | Blake Hanson | ||
| Jan. 20 | 8:30 - 8:55 a.m. | Combination Therapies for Gram-negative Bacteria | David van Duin | ||
| Jan. 20 | 2:00 - 3:00 p.m. | Session 8 | Challenging Clinical Cases in Antimicrobial Resistance | Cesar Arias | Sam Shelburne, David van Duin |
| Jan. 20 | 3:00 - 4:00 p.m. | Session 9: ARLG Session 2 Understanding the Enemy: Clinical and Microbiological Characterization of MDR Gram Negative Bacteria | Vance Fowler, Helen Boucher | ||
| Jan. 20 | 3:00 - 3:15 p.m. | Characterization of MDRO in South America | Jinnethe Reyes | ||
| Jan. 20 | 3:15 - 3:30 p.m. | SNAP International | Yohei Doi | ||
| Jan. 20 | 3:30 - 3:45 p.m. | POP International | Mike Satlin | ||
| Jan. 20 | 3:45 - 4:00 p.m. | SHREC | David van Duin | ||
| Jan. 21 | 8:35 - 9:05 a.m. | Session 11 | Keynote: Dissecting Epidemics of Multidrug-resistant Organisms | Keynote: Dissecting Epidemics of Multidrug-resistant Organisms | |
October 2021
Read the October 2021 newsletter for information on IDWeek 2021 and deadlines to apply for the Bartlett Fellowship and the Early Faculty Seedling Award. The newsletter features a spotlight on Sixto Leal, MD, PhD and his work to develop a novel diagnostic test for C. difficile as well as news on Melinda Pettigrew, PhD, who was appointed the Anna M.R. Lauder Professor of Epidemiology.
Read more from this Newsletter
Don’t miss this year’s PACCARD Public Meeting
Make time November 30 — December 1 to attend the 2021 Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (PACCARD) public meeting. The virtual event will include updates from the Global Leaders Group (GLG) and the World Health Organization (WHO) on global efforts to combat Antimicrobial Resistance (AMR). The National Academies will also discuss their recent report about the long-term health and economic effects of AMR in the United States. Day two of the event will focus on addressing AMR in pandemic planning.
Review the full meeting agenda
To attend this event, be sure to REGISTER before the November 29 deadline.
ECRAID Network Launches with Goal to Improve Efficiency of ID Clinical Trials
The launch of a new European clinical trial network in September will aid in the battle to combat antimicrobial resistance by delivering rapid, high quality research studies. The European Clinical Research Alliance for Infectious Diseases (ECRAID) features a coordinated, single-point-of-access model that aims to streamline infectious diseases research, reduce costs, and accelerate medical advancements.
The EU-funded ECRAID-Base project is supporting the ongoing development of ECRAID into an independent, self-sustaining, not-for-profit organization over the next five years.
ECRAID’s infrastructure combines networks built by the Platform for European Preparedness Against (Re-)emerging Epidemics (PREPARE) program and the Combatting Bacterial Resistance in Europe (COMBACTE) consortium. The ARLG and COMBACTE have been collaborative partners since 2019. Herman Goossens, who has been a proponent of improving European clinical trial efficiencies by increasing collaboration, is spearheading ECRAID’s vision by serving as its executive director and CEO.
ARLG at IDWeek 2021
Make the most of IDWeek 2021! From Sept. 29 – Oct. 3, ARLG’s top leaders and experts will be discussing the latest AMR topics. Use the guide below to plan your conference sessions.
ARLG IDWeek 2021 Sessions
| Day | Time | Session Title | Presentation Title | Moderators | Speakers |
|---|---|---|---|---|---|
| Sept. 29 | 4:00 - 5:15 p.m. | Chasing the Sun: CTS-06 - COVID-19 IDSA Rapid Living Guidelines: Celebrations and Challenges | COVID-19 diagnostic testing guidelines | Kim Hanson | |
| Sept. 29 | 7:00 - 8:00p.m. | Chasing the Sun: CTS-08 - COVID-19 Update in Japan | Yohei Doi | ||
| Sept. 30 | 11:00 a.m. - 12:15 p.m. | 04 - Case-based Guidelines Session | Antimicrobial Resistant Gram-Negative Infections: A Case Based Approach | Pranita Tamma | |
| Sept. 30 | 11:00 a.m. - 12:15 p.m. | 04 - Case-based Guidelines Session | Molecular Diagnostics and Antigen Testing for COVID-19 | Angela Caliendo | |
| Sept. 30 | 11:00 a.m. - 12:15 p.m. | 05 - Diagnostic Clinical Cases | Chris Doern (panelist) | ||
| Sept. 30 | 11:00a.m. - 12:15p.m. | 12 - Hot issues in Enterococcus faecalis bacteremia/endocarditis (IE) | Jose Miro | ||
| Sept. 30 | 12:30 - 1:45 p.m. | 19 - Even More Bad Bugs (with Limited Drugs) | Difficult-to-treat Resistance (DTR) Pseudomonas aeruginosa | Jessica Howard-Anderson | |
| Sept. 30 | 12:30 - 1:45 p.m. | 21 - Cardiovascular implantable electronic device (CIED) infections | Microbiological Diagnosis: Role of Advanced Diagnostics | Jose Miro | Robin Patel |
| Sept. 30 | 12:30 - 1:45 p.m. | 26 - New Approaches to the Diagnosis of Lower Respiratory Tract Infections | Next-generation Sequencing Approaches to Lower Respiratory Tract Infections | Patricia (Trish) Simner | |
| Sept. 30 | 3:45 - 5:00 p.m. | 43 – What’s New with VRE | Treatment of VRE Bacteremia: What You Need to Know | Julia Messina | Jose Munita |
| Sept. 30 | 5:15 - 6:30 p.m. | 53 - Clinical Controversies in S. aureus Bacteremia | Optimal Dosing of Antibiotics for S.aureus Bacteremia in Specific Populations | Tom Holland | Amit Pai |
| Sept. 30 | 5:15 - 6:30 p.m. | 56 - Leading Teams During a Crisis | Managing & Maintaining Priorities | Ebbing Lautenbach | |
| Oct. 1 | 10:00 - 11:15 a.m. | 61 - Do breakpoints matter? The fungal story | Breakpoints in Yeast | Mariana Castanheira | |
| Oct. 1 | 11:30 a.m. - 12:45 p.m. | 750 - Challenging cases in Infectious Diseases | Henry Chambers (interactive moderator) | ||
| Oct. 1 | 11:30 a.m. - 12:45 p.m. | 79 - Top Practice-Changing Papers on Transplant ID | Top Practice-changing Papers in Solid Organ Transplant | Judith Anesi | |
| Oct. 1 | 11:30a.m. - 12:45p.m | 85 - Public-private partnerships to revive future antibiotic development and access | Yohei Doi | ||
| Oct. 1 | 2:45 - 4:00 p.m. | 90 - Therapeutic options for MDR gram-negatives | Yohei Doi (interactive moderator) | David van Duin (panelist) | |
| Oct. 1 | 2:45 - 4:00 p.m. | 92 - Successes in Outpatient Stewardship | Sara Cosgrove | ||
| Oct. 1 | 2:45 - 4:00p.m. | 95 - Big Beasts of Skin & Soft Tissue Infections | Gram-Positive Necrotizing Soft Tissue Infections | Henry Chambers | |
| Oct. 1 | 2:45 - 4:00p.m. | 101 - Update on natural and Prosthetic Vascular Graft Infections | Jose Miro | ||
| Oct. 1 | 2:45 - 4:00 p.m. | 102 - What's New in Orthopedic Infections: Bone Appetit! | Going Viral: Phage Therapy for Orthopedic Infections | Gina Suh | |
| Oct. 1 | 4:15 - 5:30p.m. | 110 – Infectious Disease Consulting for Businesses During COVID-19: Tales from the Front Line | COVID-19 Consulting for the Entertainment Industry | Anthony Harris | |
| Oct. 2 | 10:00 - 11:15 a.m. | 127 - Pathogen-specific clinical trials: promise and practical considerations | Gram-Negative Trials: Lessons Learned | Yohei Doi | Thomas Lodise |
| Oct. 2 | 1:15 - 3:00 p.m. | 133 - Clinical Trials That May Change Your Practice | Jessica Howard-Anderson, Tom Holland |
ARLG IDWeek 2021 Posters
| Number | Title | Authors |
|---|---|---|
| 1219 | Unfavorable Clinical Outcomes with Polymyxins Compared to Ceftolozane/Tazobactam for the Treatment of Carbapenem-Resistant Pseudomonas aeruginosa | Howard-Anderson J, Earley M, Hamasaki T, Bower CW, Smith G, van Duin D, Evans S, Jacob JT |
| 1094 | Determination of Plasma Protein Binding of Dalbavancin | Turner NA, Xu A, Zaharoff S, Holland TL, Lodise TP on behalf of the Antibacterial Resistance Leadership Group |
July 2021
Our July 2021 newsletter announces an exciting new opportunity for early stage investigators, the Early Faculty Seedling Award! Read more about our fellowship’s new name honoring our colleague, mentor, and friend, John Bartlett, MD. We spotlight early stage investigator, Daria Van Tyne, feature news on Prof. Herman Goossens’ ESCMID award, and highlight a WebMD article with commentary from Vance Fowler, MD and Tori Kinamon.